Cargando…
Identification of a variant form of tyrosine phosphatase LYP
BACKGROUND: Protein tyrosine phosphatases (PTPs) are important cell signaling regulators with major pathological implications. LYP (also known as PTPN22) is an intracellular enzyme initially found to be predominately expressed in lymphocytes. Importantly, an allelic R620W variant of LYP is strongly...
Autores principales: | Wang, Shaofeng, Dong, Hongbo, Han, Jiayu, Ho, Wanting T, Fu, Xueqi, Zhao, Zhizhuang J |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987843/ https://www.ncbi.nlm.nih.gov/pubmed/21044313 http://dx.doi.org/10.1186/1471-2199-11-78 |
Ejemplares similares
-
Biochemical and Functional Studies of Lymphoid-Specific Tyrosine Phosphatase (Lyp) Variants S201F and R266W
por: Liu, Jing, et al.
Publicado: (2012) -
Loss of tyrosine phosphatase SHP2 activity promotes growth of colorectal carcinoma HCT-116 cells
por: Chen, Xin, et al.
Publicado: (2020) -
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders
por: Manso, José A., et al.
Publicado: (2022) -
Generation and characterization of a highly effective protein substrate for analysis of FLT3 activity
por: Chen, Yun, et al.
Publicado: (2012) -
JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines
por: Zhao, Wanke, et al.
Publicado: (2012)