Cargando…

Risk-reducing strategies for women carrying brca1/2 mutations with a focus on prophylactic surgery

BACKGROUND: Women who have inherited mutations in the BRCA1 or BRCA2 genes have substantially elevated risks of breast and ovarian cancer. Mutation carriers have various options, including extensive and regular surveillance, chemoprevention and risk-reducing surgery. The aim of this review is to pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salhab, Mohamed, Bismohun, Selina, Mokbel, Kefah
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987888/ https://www.ncbi.nlm.nih.gov/pubmed/20961453 http://dx.doi.org/10.1186/1472-6874-10-28

Ejemplares similares

Risk-reducing surgery in BRCA 1/2 mutation carries: a point of view
por: De Felice, Francesca, et al.
Publicado: (2015)

Prediction of carrying a BRCA1 or BRCA2 mutation
por: Lee, Kyung-Hun
Publicado: (2023)

Evolving Trends in Breast Surgery: Oncoplastic to Onco-Aesthetic Surgery
por: Carmichael, Amtul R, et al.
Publicado: (2016)

Estimates of the likely prophylactic effect of tamoxifen in women with high risk BRCA1 and BRCA2 mutations
por: Duffy, S W, et al.
Publicado: (2002)

The Effect of Prophylactic Adnexectomy on the Quality of Life and Psychosocial Functioning of Women with the BRCA1/BRCA2 Mutations
por: Stanisz, Marta, et al.
Publicado: (2019)

The association between telomerase activity and expression of its RNA component (hTR) in breast cancer patients: the importance of DNase treatment
por: Hosseini-Asl, Saied, et al.
Publicado: (2006)

The expression of hTR and hTERT in human breast cancer: correlation with clinico-pathological parameters
por: Hosseini-Asl, Saied, et al.
Publicado: (2006)

Exploring the interface zone in breast cancer: implications for surgical strategies and beyond
por: Mokbel, Kefah, et al.
Publicado: (2023)

Response to Letter: Evolving Trends in Breast Surgery: Oncoplastic to Onco-Aesthetic Surgery
por: Carmichael, Amtul Razzaq, et al.
Publicado: (2017)

Evidence for accelerated aging in mammary epithelia of women carrying germline BRCA1 or BRCA2 mutations
por: Shalabi, Sundus F., et al.
Publicado: (2021)

Physical activity and sleep behaviour in women carrying BRCA1/2 mutations
por: Galasso, Letizia, et al.
Publicado: (2022)

Does the timing of breast cancer surgery in pre-menopausal women affect clinical outcome? : an update
por: Chaudhry, Anushka, et al.
Publicado: (2006)

Variation in rates of uptake of preventive options by Canadian women carrying the BRCA1 or BRCA2 genetic mutation
por: Metcalfe, Kelly A, et al.
Publicado: (2007)

Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older women
por: Sidon, L, et al.
Publicado: (2012)

Simultaneous Salvage Auto-augmentation: Contemporary Strategy for Management of the Breast Explantation Patient
por: Kirwan, Laurence, et al.
Publicado: (2023)

Capsular contraction following immediate reconstructive surgery for breast cancer – An association with methylene blue dye
por: Singh-Ranger, Gurpreet, et al.
Publicado: (2004)

Prophylactic Surgery in the BRCA+ Patient: Do Women Develop Breast Cancer While Waiting?
por: Macadam, Sheina A., et al.
Publicado: (2021)

Skin-sparing mastectomy and radiotherapy: an update
por: Mokbel, Ramia, et al.
Publicado: (2006)

The Evolving Role of Radiofrequency Guided Localisation in Breast Surgery: A Systematic Review
por: Tayeh, Salim, et al.
Publicado: (2021)

Clinical outcome for BRCA1 and BRCA2 mutation carriers after contralateral prophylactic mastectomy
por: Schmidt, MK, et al.
Publicado: (2005)

Author Correction: Physical activity and sleep behaviour in women carrying BRCA1/2 mutations
por: Galasso, Letizia, et al.
Publicado: (2022)

Breast weight and hormone receptor status in women with breast cancer
por: Salhab, M, et al.
Publicado: (2005)

Prophylactic and Therapeutic Breast Conservation in BRCA1/2 Mutation Carriers
por: Croshaw, Randal L., et al.
Publicado: (2011)

Adjuvant endocrine therapy for postmenopausal breast cancer in the era of aromatase inhibitors: an update
por: Mokbel, Ramia, et al.
Publicado: (2006)

Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation in Asian breast cancer patients
por: Ang, Boon Hong, et al.
Publicado: (2022)

Clinical outcome of prophylactic oophorectomy in BRCA1/BRCA2 mutation carriers and events during follow-up
por: Olivier, R I, et al.
Publicado: (2004)

MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary
por: Lee, Cheng-Han, et al.
Publicado: (2009)

Evaluation of the indication of BRCA1/2 genetic tests in Iranian women and acceptance rate of risk‐reducing surgeries in BRCA mutation carriers
por: Vasigh, Mahtab, et al.
Publicado: (2022)

The role of Herceptin in early breast cancer
por: Subramanian, Ashok, et al.
Publicado: (2008)

Redefining axillary lymph node dissection in mastectomy: insights from the SINODAR-ONE study
por: Mokbel, Kefah, et al.
Publicado: (2023)

Is there a difference in testosterone levels and its regulators in men carrying BRCA mutations?
por: Goldberg, Hanan, et al.
Publicado: (2017)

Are online prediction tools a valid alternative to genomic profiling in the context of systemic treatment of ER-positive breast cancer?
por: Wazir, Umar, et al.
Publicado: (2017)

Is preoperative core biopsy accurate in determining the hormone receptor status in women with invasive breast cancer?
por: Al Sarakbi, W, et al.
Publicado: (2005)

Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer
por: Kiely, B. E., et al.
Publicado: (2011)

Locoregional therapy in de novo metastatic breast cancer. The unanswered question
por: Cardoso, Maria-Joao, et al.
Publicado: (2021)

Risk reduction of contralateral breast cancer and survival after contralateral prophylactic mastectomy in BRCA1 or BRCA2 mutation carriers
por: van Sprundel, T C, et al.
Publicado: (2005)

International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation
por: Metcalfe, Kelly, et al.
Publicado: (2019)

Pathologic Findings at Risk Reducing Surgery in BRCA and Non-BRCA Mutation Carriers: A Single-Center Experience
por: Cassani, Chiara, et al.
Publicado: (2022)

The expression of BRCA1, P53, KAI1, and Nm23 in ovaries of BRCA1 mutation carriers after prophylactic adnexectomy
por: Markowska, J., et al.
Publicado: (2013)

Penetrance of Breast and Ovarian Cancer in Women Who Carry a BRCA1/2 Mutation and Do Not Use Risk-Reducing Salpingo-Oophorectomy: An Updated Meta-Analysis
por: Chen, Jinbo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5a8sfhldijnnvjq81phfei3fs0