Genome-Wide Association Study Identifies Two Novel Regions at 11p15.5-p13 and 1p31 with Major Impact on Acute-Phase Serum Amyloid A

Elevated levels of acute-phase serum amyloid A (A-SAA) cause amyloidosis and are a risk factor for atherosclerosis and its clinical complications, type 2 diabetes, as well as various malignancies. To investigate the genetic basis of A-SAA levels, we conducted the first genome-wide association study...

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Detalles Bibliográficos
Autores principales: Marzi, Carola, Albrecht, Eva, Hysi, Pirro G., Lagou, Vasiliki, Waldenberger, Melanie, Tönjes, Anke, Prokopenko, Inga, Heim, Katharina, Blackburn, Hannah, Ried, Janina S., Kleber, Marcus E., Mangino, Massimo, Thorand, Barbara, Peters, Annette, Hammond, Christopher J., Grallert, Harald, Boehm, Bernhard O., Kovacs, Peter, Geistlinger, Ludwig, Prokisch, Holger, Winkelmann, Bernhard R., Spector, Tim D., Wichmann, H.-Erich, Stumvoll, Michael, Soranzo, Nicole, März, Winfried, Koenig, Wolfgang, Illig, Thomas, Gieger, Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987930/
https://www.ncbi.nlm.nih.gov/pubmed/21124955
http://dx.doi.org/10.1371/journal.pgen.1001213

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