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Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells

BACKGROUND: Advanced glycation products (AGEs), as endogenous inflammatory mediator, compromise the physiological function of mesenchymal stem cells (MSCs). MSCs have a potential role in cell replacement therapy in acute myocardial infarction and ischemic cardiomyopathy. However, mechanisms of AGEs...

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Detalles Bibliográficos
Autores principales:	Yang, Ke, Wang, Xiao Qun, He, Yu Song, Lu, Lin, Chen, Qiu Jing, Liu, Jing, Shen, Wei Feng
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987998/ https://www.ncbi.nlm.nih.gov/pubmed/20969783 http://dx.doi.org/10.1186/1475-2840-9-66

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