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Potential pitfalls in MitoChip detected tumor-specific somatic mutations: a call for caution when interpreting patient data
BACKGROUND: Several investigators have employed high throughput mitochondrial sequencing array (MitoChip) in clinical studies to search mtDNA for markers linked to cancers. In consequence, a host of somatic mtDNA mutations have been identified as linked to different types of cancers. However, closer...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988032/ https://www.ncbi.nlm.nih.gov/pubmed/21034508 http://dx.doi.org/10.1186/1471-2407-10-597 |