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Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border

BACKGROUND: Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug...

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Detalles Bibliográficos
Autores principales:	Takeuchi, Rie, Lawpoolsri, Saranath, Imwong, Mallika, Kobayashi, Jun, Kaewkungwal, Jaranit, Pukrittayakamee, Sasithon, Puangsa-art, Supalap, Thanyavanich, Nipon, Maneeboonyang, Wanchai, Day, Nicholas PJ, Singhasivanon, Pratap
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988041/ https://www.ncbi.nlm.nih.gov/pubmed/21040545 http://dx.doi.org/10.1186/1475-2875-9-308

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