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Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease

BACKGROUND: It is hypothesized that complex interactions between multiple environmental factors and genetic factors are implicated in sporadic Alzheimer's disease (AD); however, the underlying mechanisms are poorly understood. Importantly, recent evidence reveals that expression and activity le...

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Detalles Bibliográficos
Autores principales: Devi, Latha, Alldred, Melissa J, Ginsberg, Stephen D, Ohno, Masuo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988063/
https://www.ncbi.nlm.nih.gov/pubmed/21059265
http://dx.doi.org/10.1186/1756-6606-3-34