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Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial
BACKGROUND: Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefits is uncertain. We aimed to establish efficacy and safety of more intensive statin treatment in patients at high cardiovascular risk. METHODS: We undertook a double-...
Autor principal: | Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Lancet Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988223/ https://www.ncbi.nlm.nih.gov/pubmed/21067805 http://dx.doi.org/10.1016/S0140-6736(10)60310-8 |
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