Cargando…

PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC

Twenty four patients meeting R.D.C. criteria for schizophrenia were assessed using the B.P.R.S. before starting neuroleptics. They were then given a standardized test dose of haloperidol. Their subjective response to the test dose was assessed 4 hours later by a blind rater. The B.P.R.S. ratings wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Borde, Milind, Davis, Elizabeth J.B., Sharma, L.N.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988291/
https://www.ncbi.nlm.nih.gov/pubmed/21897458
_version_ 1782192239521300480
author Borde, Milind
Davis, Elizabeth J.B.
Sharma, L.N.
author_facet Borde, Milind
Davis, Elizabeth J.B.
Sharma, L.N.
author_sort Borde, Milind
collection PubMed
description Twenty four patients meeting R.D.C. criteria for schizophrenia were assessed using the B.P.R.S. before starting neuroleptics. They were then given a standardized test dose of haloperidol. Their subjective response to the test dose was assessed 4 hours later by a blind rater. The B.P.R.S. ratings were repeated after 3 weeks of neuroleptic treatment. A dysphoric response to the test dose was associated with a poor therapeutic outcome. The implications of these findings are discussed.
format Text
id pubmed-2988291
institution National Center for Biotechnology Information
language English
publishDate 1991
publisher Medknow Publications
record_format MEDLINE/PubMed
spelling pubmed-29882912011-09-06 PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC Borde, Milind Davis, Elizabeth J.B. Sharma, L.N. Indian J Psychiatry Original Article Twenty four patients meeting R.D.C. criteria for schizophrenia were assessed using the B.P.R.S. before starting neuroleptics. They were then given a standardized test dose of haloperidol. Their subjective response to the test dose was assessed 4 hours later by a blind rater. The B.P.R.S. ratings were repeated after 3 weeks of neuroleptic treatment. A dysphoric response to the test dose was associated with a poor therapeutic outcome. The implications of these findings are discussed. Medknow Publications 1991 /pmc/articles/PMC2988291/ /pubmed/21897458 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Borde, Milind
Davis, Elizabeth J.B.
Sharma, L.N.
PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC
title PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC
title_full PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC
title_fullStr PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC
title_full_unstemmed PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC
title_short PREDICTION OF OUTCOME IN SCHIZOPHRENIA USING THE SUBJECTIVE RESPONSE TO A TEST DOSE OF A NEUROLEPTIC
title_sort prediction of outcome in schizophrenia using the subjective response to a test dose of a neuroleptic
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988291/
https://www.ncbi.nlm.nih.gov/pubmed/21897458
work_keys_str_mv AT bordemilind predictionofoutcomeinschizophreniausingthesubjectiveresponsetoatestdoseofaneuroleptic
AT daviselizabethjb predictionofoutcomeinschizophreniausingthesubjectiveresponsetoatestdoseofaneuroleptic
AT sharmaln predictionofoutcomeinschizophreniausingthesubjectiveresponsetoatestdoseofaneuroleptic