A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION

This report describes the results of a multicentre collaborative study comparing the safety and efficacy of alprazolam with imipramine in patients suffering from major depressive disorder. Two hundred and eight patients diagnosed as major depression as per DSM-III criteria were randomly allocated to...

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Autores principales: Murthy, R.S., Chatterjee, Somanath, Sriram, T.G., Shah, L.P., Parikh, Rajesh, Elavia, S., Munjal, G.C., Nehru, Ravi, Ramachandran, V., Nirmala, G., Raghavan, K.S., Kumar, V.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1991
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988295/
https://www.ncbi.nlm.nih.gov/pubmed/21897464
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author Murthy, R.S.
Chatterjee, Somanath
Sriram, T.G.
Shah, L.P.
Parikh, Rajesh
Elavia, S.
Munjal, G.C.
Nehru, Ravi
Ramachandran, V.
Nirmala, G.
Raghavan, K.S.
Kumar, V.
author_facet Murthy, R.S.
Chatterjee, Somanath
Sriram, T.G.
Shah, L.P.
Parikh, Rajesh
Elavia, S.
Munjal, G.C.
Nehru, Ravi
Ramachandran, V.
Nirmala, G.
Raghavan, K.S.
Kumar, V.
author_sort Murthy, R.S.
collection PubMed
description This report describes the results of a multicentre collaborative study comparing the safety and efficacy of alprazolam with imipramine in patients suffering from major depressive disorder. Two hundred and eight patients diagnosed as major depression as per DSM-III criteria were randomly allocated to alprazolam (N= 105) or imipramine (N = 103) in a double-blind fashion. Detailed assessments were carried out for a period of six weeks. Results revealed that alprazolam was as effective as imipramine as an antidepressant. Side effects were less frequently reported with alprazolam.
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spelling pubmed-29882952011-09-06 A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION Murthy, R.S. Chatterjee, Somanath Sriram, T.G. Shah, L.P. Parikh, Rajesh Elavia, S. Munjal, G.C. Nehru, Ravi Ramachandran, V. Nirmala, G. Raghavan, K.S. Kumar, V. Indian J Psychiatry Original Article This report describes the results of a multicentre collaborative study comparing the safety and efficacy of alprazolam with imipramine in patients suffering from major depressive disorder. Two hundred and eight patients diagnosed as major depression as per DSM-III criteria were randomly allocated to alprazolam (N= 105) or imipramine (N = 103) in a double-blind fashion. Detailed assessments were carried out for a period of six weeks. Results revealed that alprazolam was as effective as imipramine as an antidepressant. Side effects were less frequently reported with alprazolam. Medknow Publications 1991 /pmc/articles/PMC2988295/ /pubmed/21897464 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Murthy, R.S.
Chatterjee, Somanath
Sriram, T.G.
Shah, L.P.
Parikh, Rajesh
Elavia, S.
Munjal, G.C.
Nehru, Ravi
Ramachandran, V.
Nirmala, G.
Raghavan, K.S.
Kumar, V.
A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION
title A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION
title_full A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION
title_fullStr A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION
title_full_unstemmed A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION
title_short A DOUBLE-BLIND EVALUATION OF ALPRAZOLAM AND IMIPRAMINE IN THE TREATMENT OF MAJOR DEPRESSION
title_sort double-blind evaluation of alprazolam and imipramine in the treatment of major depression
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988295/
https://www.ncbi.nlm.nih.gov/pubmed/21897464
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