LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

The serine/threonine kinase LKB1 has a conserved role in Drosophila and nematodes to co-ordinate cell metabolism. During T lymphocyte development in the thymus, progenitors need to synchronize increased metabolism with the onset of proliferation and differentiation to ensure that they can meet the e...

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Detalles Bibliográficos
Autores principales: Tamás, Peter, Macintyre, Andrew, Finlay, David, Clarke, Rosemary, Feijoo-Carnero, Carmen, Ashworth, Alan, Cantrell, Doreen
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Molecular Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988414/
https://www.ncbi.nlm.nih.gov/pubmed/19830737
http://dx.doi.org/10.1002/eji.200939677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988414/
https://www.ncbi.nlm.nih.gov/pubmed/19830737
http://dx.doi.org/10.1002/eji.200939677

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