The frequency of NPM1 mutations in childhood acute myeloid leukemia

BACKGROUND: Mutations in the nucleophosmin (NPM1) gene have been solely associated with childhood acute myeloid leukemia (AML). We evaluated the frequency of NPM1 mutations in childhood AML, their relation to clinical and cytogenetic features and the presence of common FLT3 and RAS mutations. RESULT...

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Detalles Bibliográficos
Autores principales: Braoudaki, Maria, Papathanassiou, Chrissa, Katsibardi, Katerina, Tourkadoni, Natalia, Karamolegou, Kalliopi, Tzortzatou-Stathopoulou, Fotini
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988697/
https://www.ncbi.nlm.nih.gov/pubmed/20979630
http://dx.doi.org/10.1186/1756-8722-3-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988697/
https://www.ncbi.nlm.nih.gov/pubmed/20979630
http://dx.doi.org/10.1186/1756-8722-3-41

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