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Human ASPM participates in spindle organisation, spindle orientation and cytokinesis

BACKGROUND: Mutations in the Abnormal Spindle Microcephaly related gene (ASPM) are the commonest cause of autosomal recessive primary microcephaly (MCPH) a disorder characterised by a small brain and associated mental retardation. ASPM encodes a mitotic spindle pole associated protein. It is suggest...

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Detalles Bibliográficos
Autores principales:	Higgins, Julie, Midgley, Carol, Bergh, Anna-Maria, Bell, Sandra M, Askham, Jonathan M, Roberts, Emma, Binns, Ruth K, Sharif, Saghira M, Bennett, Christopher, Glover, David M, Woods, C Geoffrey, Morrison, Ewan E, Bond, Jacquelyn
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988714/ https://www.ncbi.nlm.nih.gov/pubmed/21044324 http://dx.doi.org/10.1186/1471-2121-11-85

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