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Evaluation of six CTLA-4 polymorphisms in high-risk melanoma patients receiving adjuvant interferon therapy in the He13A/98 multicenter trial
PURPOSE: Interferon is approved for adjuvant treatment of patients with stage IIb/III melanoma. The toxicity and uncertainty regarding survival benefits of interferon have qualified its acceptance, despite significant durable relapse prevention in a fraction of patients. Predictive biomarkers that w...
Autores principales: | Gogas, Helen, Dafni, Urania, Koon, Henry, Spyropoulou-Vlachou, Maria, Metaxas, Yannis, Buchbinder, Elizabeth, Pectasides, Eirini, Tsoutsos, Dimosthenis, Polyzos, Aristidis, Stratigos, Alexandros, Markopoulos, Christos, Panagiotou, Petros, Fountzilas, George, Castana, Ourania, Skarlos, Pantelis, Atkins, Michael B, Kirkwood, John M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988721/ https://www.ncbi.nlm.nih.gov/pubmed/21044351 http://dx.doi.org/10.1186/1479-5876-8-108 |
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