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Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols
BACKGROUND: Health Related Quality of Life has been used in medical research for more than twenty years, being progressively accepted during the last decade as an important patient reported outcome. Considering the multidimensional approach involved in Health Related Quality of Life assessment, inst...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988779/ https://www.ncbi.nlm.nih.gov/pubmed/21040524 http://dx.doi.org/10.1186/1758-3284-2-32 |
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author | Silveira, Augusta P Gonçalves, Joaquim Sequeira, Teresa Ribeiro, Cláudia Lopes, Carlos Monteiro, Eurico Pimentel, Francisco L |
author_facet | Silveira, Augusta P Gonçalves, Joaquim Sequeira, Teresa Ribeiro, Cláudia Lopes, Carlos Monteiro, Eurico Pimentel, Francisco L |
author_sort | Silveira, Augusta P |
collection | PubMed |
description | BACKGROUND: Health Related Quality of Life has been used in medical research for more than twenty years, being progressively accepted during the last decade as an important patient reported outcome. Considering the multidimensional approach involved in Health Related Quality of Life assessment, instrument applicability and cultural adaptation must be tested for each population. In order to select the most appropriate instrument for Head and Neck cancer patients, two major Health Related Quality of Life specific questionnaires for Head and Neck cancer patients were compared. Conceptual differences, psychometric characteristics, scores, reliability, construct validity and sensitivity to symptomatology, tumour location, tumour size were analyzed. METHODS: 102 consecutive Head and Neck cancer patients completed two different Health Related Quality of Life questionnaires: EORTC QLQ-C30 and its specific head and neck module QLQ-H&N35 and the Functional Assessment of Cancer Therapy Scales (FACT-H&N). Patients completed the questionnaires, immediately before consultation as a part of the routine evaluation. RESULTS: A greater variability was always found in the EORTC QLC-C30 questionnaire's scores for all comparable domains. Both instruments revealed a good internal consistency and demonstrated to be good tools to distinguish symptomatic patients. The EORTC questionnaires still demonstrated sensitivity to distinguish T3 and T4 staging. Conceptual differences and the psychometric characteristics are discussed. Our results suggest that these two instruments assess different aspects of Health Related Quality of Life - the questionnaires should be used separately and chosen according to the study objectives and methodology. CONCLUSIONS: This study emphases the importance in selecting the appropriate tool as a critical success factor in implementing routine Health Related Quality of Life assessment in clinical practice. This decision assumes particularly importance when utilization of results in real time and integration into clinical protocols are considered. |
format | Text |
id | pubmed-2988779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-29887792010-11-20 Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols Silveira, Augusta P Gonçalves, Joaquim Sequeira, Teresa Ribeiro, Cláudia Lopes, Carlos Monteiro, Eurico Pimentel, Francisco L Head Neck Oncol Research BACKGROUND: Health Related Quality of Life has been used in medical research for more than twenty years, being progressively accepted during the last decade as an important patient reported outcome. Considering the multidimensional approach involved in Health Related Quality of Life assessment, instrument applicability and cultural adaptation must be tested for each population. In order to select the most appropriate instrument for Head and Neck cancer patients, two major Health Related Quality of Life specific questionnaires for Head and Neck cancer patients were compared. Conceptual differences, psychometric characteristics, scores, reliability, construct validity and sensitivity to symptomatology, tumour location, tumour size were analyzed. METHODS: 102 consecutive Head and Neck cancer patients completed two different Health Related Quality of Life questionnaires: EORTC QLQ-C30 and its specific head and neck module QLQ-H&N35 and the Functional Assessment of Cancer Therapy Scales (FACT-H&N). Patients completed the questionnaires, immediately before consultation as a part of the routine evaluation. RESULTS: A greater variability was always found in the EORTC QLC-C30 questionnaire's scores for all comparable domains. Both instruments revealed a good internal consistency and demonstrated to be good tools to distinguish symptomatic patients. The EORTC questionnaires still demonstrated sensitivity to distinguish T3 and T4 staging. Conceptual differences and the psychometric characteristics are discussed. Our results suggest that these two instruments assess different aspects of Health Related Quality of Life - the questionnaires should be used separately and chosen according to the study objectives and methodology. CONCLUSIONS: This study emphases the importance in selecting the appropriate tool as a critical success factor in implementing routine Health Related Quality of Life assessment in clinical practice. This decision assumes particularly importance when utilization of results in real time and integration into clinical protocols are considered. BioMed Central 2010-10-31 /pmc/articles/PMC2988779/ /pubmed/21040524 http://dx.doi.org/10.1186/1758-3284-2-32 Text en Copyright ©2010 Silveira et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Silveira, Augusta P Gonçalves, Joaquim Sequeira, Teresa Ribeiro, Cláudia Lopes, Carlos Monteiro, Eurico Pimentel, Francisco L Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
title | Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
title_full | Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
title_fullStr | Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
title_full_unstemmed | Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
title_short | Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
title_sort | patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988779/ https://www.ncbi.nlm.nih.gov/pubmed/21040524 http://dx.doi.org/10.1186/1758-3284-2-32 |
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