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An Essential Role of the Cytoplasmic Tail of CXCR4 in G-Protein Signaling and Organogenesis
CXCR4 regulates cell proliferation, enhances cell survival and induces chemotaxis, yet molecular mechanisms underlying its signaling remain elusive. Like all other G-protein coupled receptors (GPCRs), CXCR4 delivers signals through G-protein-dependent and -independent pathways, the latter involving...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988825/ https://www.ncbi.nlm.nih.gov/pubmed/21124917 http://dx.doi.org/10.1371/journal.pone.0015397 |