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Ephedra-Induced Gastric Mucosal Injury
In this case report we detail the difficult case of a 74-year-old male patient who was transferred to our cardiac intensive care unit in severe shock with an acute abdomen. His abdomen was emergently explored revealing isolated gastric necrosis and ischemia. A subtotal gastrectomy was performed and...
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Formato: | Texto |
Lenguaje: | English |
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S. Karger AG
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988902/ https://www.ncbi.nlm.nih.gov/pubmed/21103232 http://dx.doi.org/10.1159/000262290 |
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author | Lillegard, Joseph B. Porterfield Jr., John R. |
author_facet | Lillegard, Joseph B. Porterfield Jr., John R. |
author_sort | Lillegard, Joseph B. |
collection | PubMed |
description | In this case report we detail the difficult case of a 74-year-old male patient who was transferred to our cardiac intensive care unit in severe shock with an acute abdomen. His abdomen was emergently explored revealing isolated gastric necrosis and ischemia. A subtotal gastrectomy was performed and the patient was discharged from the hospital 34 days after surgery. Postoperatively we learned that for the preceding 2 weeks the patient had doubled the dose of Forcalide syrup which he had been taking for his reactive airway disease for many years. Formal testing of this fluid revealed a concentrated sugar-based solution with a high concentration of both Ephedra and potassium chloride. Final pathology of the resected stomach demonstrated patent vessels to the stomach with extensive microvascular thrombosis and full-thickness gastric necrosis. On final summation of this case we concluded that the Ephedra in the patient's Forcalide syrup caused the microvascular necrosis seen in the stomach and should be added to the list of potential adverse reactions seen with the ingestion of ephedrine. |
format | Text |
id | pubmed-2988902 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-29889022010-11-22 Ephedra-Induced Gastric Mucosal Injury Lillegard, Joseph B. Porterfield Jr., John R. Case Rep Gastroenterol Published: February 2010 In this case report we detail the difficult case of a 74-year-old male patient who was transferred to our cardiac intensive care unit in severe shock with an acute abdomen. His abdomen was emergently explored revealing isolated gastric necrosis and ischemia. A subtotal gastrectomy was performed and the patient was discharged from the hospital 34 days after surgery. Postoperatively we learned that for the preceding 2 weeks the patient had doubled the dose of Forcalide syrup which he had been taking for his reactive airway disease for many years. Formal testing of this fluid revealed a concentrated sugar-based solution with a high concentration of both Ephedra and potassium chloride. Final pathology of the resected stomach demonstrated patent vessels to the stomach with extensive microvascular thrombosis and full-thickness gastric necrosis. On final summation of this case we concluded that the Ephedra in the patient's Forcalide syrup caused the microvascular necrosis seen in the stomach and should be added to the list of potential adverse reactions seen with the ingestion of ephedrine. S. Karger AG 2010-02-27 /pmc/articles/PMC2988902/ /pubmed/21103232 http://dx.doi.org/10.1159/000262290 Text en Copyright © 2010 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: February 2010 Lillegard, Joseph B. Porterfield Jr., John R. Ephedra-Induced Gastric Mucosal Injury |
title | Ephedra-Induced Gastric Mucosal Injury |
title_full | Ephedra-Induced Gastric Mucosal Injury |
title_fullStr | Ephedra-Induced Gastric Mucosal Injury |
title_full_unstemmed | Ephedra-Induced Gastric Mucosal Injury |
title_short | Ephedra-Induced Gastric Mucosal Injury |
title_sort | ephedra-induced gastric mucosal injury |
topic | Published: February 2010 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988902/ https://www.ncbi.nlm.nih.gov/pubmed/21103232 http://dx.doi.org/10.1159/000262290 |
work_keys_str_mv | AT lillegardjosephb ephedrainducedgastricmucosalinjury AT porterfieldjrjohnr ephedrainducedgastricmucosalinjury |