Robust Cardiomyocyte-Specific Gene Expression Following Systemic Injection of AAV: In Vivo Gene Delivery Follows a Poisson Distribution

Newly-isolated serotypes of AAV readily cross the endothelial barrier to provide efficient transgene delivery throughout the body. However, tissue-specific expression is preferred in most experimental studies and gene therapy protocols. Previous efforts to restrict gene expression to the myocardium...

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Detalles Bibliográficos
Autores principales: Prasad, Konkal-Matt R., Xu, Yaqin, Yang, Zequan, Acton, Scott T., French, Brent A
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988989/
https://www.ncbi.nlm.nih.gov/pubmed/20703310
http://dx.doi.org/10.1038/gt.2010.105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988989/
https://www.ncbi.nlm.nih.gov/pubmed/20703310
http://dx.doi.org/10.1038/gt.2010.105

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