Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats

BACKGROUND: The Orf virus (ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochth...

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Autores principales: Lojkic, Ivana, Cac, Zeljko, Beck, Ana, Bedekovic, Tomislav, Cvetnic, Zeljko, Sostaric, Branko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989325/
https://www.ncbi.nlm.nih.gov/pubmed/21073725
http://dx.doi.org/10.1186/1743-422X-7-314
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author Lojkic, Ivana
Cac, Zeljko
Beck, Ana
Bedekovic, Tomislav
Cvetnic, Zeljko
Sostaric, Branko
author_facet Lojkic, Ivana
Cac, Zeljko
Beck, Ana
Bedekovic, Tomislav
Cvetnic, Zeljko
Sostaric, Branko
author_sort Lojkic, Ivana
collection PubMed
description BACKGROUND: The Orf virus (ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochthonous Croatian Cres-breed sheep and ii) on small family goat farm. RESULTS: Sequence and phylogenetic analyses of the ORFV B2L gene showed that the Cro-Cres-12446/09 and Cro-Goat-11727/10 were not clustered together. Cro-Cres-12446/09 shared the highest similarity with ORFV NZ2 from New Zealand, and Ena from Japan; Cro-Goat-11727/10 was closest to the HuB from China and Taiping and Hoping from Taiwan. CONCLUSION: Distinct ORFV strains are circulating in Croatia. Although ORFV infections are found ubiquitously wherever sheep and goats are farmed in Croatia, this is the first information on genetic relatedness of any Croatian ORFV with other isolates around the world.
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spelling pubmed-29893252010-11-21 Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats Lojkic, Ivana Cac, Zeljko Beck, Ana Bedekovic, Tomislav Cvetnic, Zeljko Sostaric, Branko Virol J Research BACKGROUND: The Orf virus (ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochthonous Croatian Cres-breed sheep and ii) on small family goat farm. RESULTS: Sequence and phylogenetic analyses of the ORFV B2L gene showed that the Cro-Cres-12446/09 and Cro-Goat-11727/10 were not clustered together. Cro-Cres-12446/09 shared the highest similarity with ORFV NZ2 from New Zealand, and Ena from Japan; Cro-Goat-11727/10 was closest to the HuB from China and Taiping and Hoping from Taiwan. CONCLUSION: Distinct ORFV strains are circulating in Croatia. Although ORFV infections are found ubiquitously wherever sheep and goats are farmed in Croatia, this is the first information on genetic relatedness of any Croatian ORFV with other isolates around the world. BioMed Central 2010-11-12 /pmc/articles/PMC2989325/ /pubmed/21073725 http://dx.doi.org/10.1186/1743-422X-7-314 Text en Copyright ©2010 Lojkic et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Lojkic, Ivana
Cac, Zeljko
Beck, Ana
Bedekovic, Tomislav
Cvetnic, Zeljko
Sostaric, Branko
Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_full Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_fullStr Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_full_unstemmed Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_short Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats
title_sort phylogenetic analysis of croatian orf viruses isolated from sheep and goats
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989325/
https://www.ncbi.nlm.nih.gov/pubmed/21073725
http://dx.doi.org/10.1186/1743-422X-7-314
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