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Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease
Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 d...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989382/ https://www.ncbi.nlm.nih.gov/pubmed/21113297 http://dx.doi.org/10.4061/2011/242353 |
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author | Takenaka, Tsuneo Sato, Takahiko Hoshi, Hitoshi Kato, Nobutaka Sueyoshi, Keita Tsuda, Masahiro Watanabe, Yusuke Takane, Hiroshi Ohno, Yoichi Suzuki, Hiromichi |
author_facet | Takenaka, Tsuneo Sato, Takahiko Hoshi, Hitoshi Kato, Nobutaka Sueyoshi, Keita Tsuda, Masahiro Watanabe, Yusuke Takane, Hiroshi Ohno, Yoichi Suzuki, Hiromichi |
author_sort | Takenaka, Tsuneo |
collection | PubMed |
description | Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. In addition to AI estimated with radial artery tonometry, classical cardiovascular risk factors were considered. Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. Conclusions. Our findings provide new evidence that shortness in height independently contributes to total mortality in hemodialysis patients. |
format | Text |
id | pubmed-2989382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-29893822010-11-26 Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease Takenaka, Tsuneo Sato, Takahiko Hoshi, Hitoshi Kato, Nobutaka Sueyoshi, Keita Tsuda, Masahiro Watanabe, Yusuke Takane, Hiroshi Ohno, Yoichi Suzuki, Hiromichi Cardiol Res Pract Clinical Study Aim. Height is an important determinant of augmentation index (AI) that anticipates cardiovascular prognosis. There is a scanty of the data whether short height predicts survival in patients with end-stage renal diseases, a high risk population. Methods. Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. In addition to AI estimated with radial artery tonometry, classical cardiovascular risk factors were considered. Patients were followed for 2 years to assess cardiovascular prognosis. Results. Cox hazards regression revealed that both smoking and shortness in height independently contributed to total mortality and indicated that smoking as well as the presence of left ventricular hypertrophy predicted cardiovascular mortality. Our findings implicated that high AI, the presence of diabetes, and low high-density lipoprotein cholesterol were significant contributors to cardiovascular events. Conclusions. Our findings provide new evidence that shortness in height independently contributes to total mortality in hemodialysis patients. SAGE-Hindawi Access to Research 2010-11-11 /pmc/articles/PMC2989382/ /pubmed/21113297 http://dx.doi.org/10.4061/2011/242353 Text en Copyright © 2011 Tsuneo Takenaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Takenaka, Tsuneo Sato, Takahiko Hoshi, Hitoshi Kato, Nobutaka Sueyoshi, Keita Tsuda, Masahiro Watanabe, Yusuke Takane, Hiroshi Ohno, Yoichi Suzuki, Hiromichi Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title | Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_full | Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_fullStr | Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_full_unstemmed | Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_short | Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease |
title_sort | height constitutes an important predictor of mortality in end-stage renal disease |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989382/ https://www.ncbi.nlm.nih.gov/pubmed/21113297 http://dx.doi.org/10.4061/2011/242353 |
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