A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation

X-linked mental retardation (XLMR) is an inherited disorder that mostly affects males and is caused by mutations in genes located on the X chromosome. Here, we show that the XLMR protein PHF8 and a C. elegans homolog F29B9.2 catalyze demethylation of di- and monomethylated lysine 9 of histone H3 (H3...

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Detalles Bibliográficos
Autores principales: Kleine-Kohlbrecher, Daniela, Christensen, Jesper, Vandamme, Julien, Abarrategui, Iratxe, Bak, Mads, Tommerup, Niels, Shi, Xiaobing, Gozani, Or, Rappsilber, Juri, Salcini, Anna Elisabetta, Helin, Kristian
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989439/
https://www.ncbi.nlm.nih.gov/pubmed/20346720
http://dx.doi.org/10.1016/j.molcel.2010.03.002

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