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Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation
Antigen-specific proliferation is a critical function of memory T cells that is often utilised to measure vaccine immunogenicity and T cell function. We proposed that measurement of intracellular expression of the nuclear protein, Ki67, could reliably assess specific T cell proliferation in vitro. K...
Autores principales: | Soares, Andreia, Govender, Lerisa, Hughes, Jane, Mavakla, Wendy, de Kock, Marwou, Barnard, Charlene, Pienaar, Bernadette, Janse van Rensburg, Esme, Jacobs, Gail, Khomba, Gloria, Stone, Lynnette, Abel, Brian, Scriba, Thomas J., Hanekom, Willem A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989440/ https://www.ncbi.nlm.nih.gov/pubmed/20800066 http://dx.doi.org/10.1016/j.jim.2010.08.007 |
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