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Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence Requirement

Although MMP-28 is involved in numerous important physiologic and pathologic conditions, the mechanisms of action of this secreted proteinase is not well understood. We now have demonstrated that furin serves as an intermolecular chaperone for MMP-28 secretion by interacting with the propeptide doma...

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Detalles Bibliográficos
Autores principales:	Pavlaki, Maria, Zucker, Stanley, Dufour, Antoine, Calabrese, Nikki, Bahou, Wadie, Cao, Jian
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989691/ https://www.ncbi.nlm.nih.gov/pubmed/21152186 http://dx.doi.org/10.1155/2011/630319

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