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Cytomegalovirus immunoevasin reveals the physiological role of “missing self” recognition in natural killer cell dependent virus control in vivo

Cytomegaloviruses (CMVs) are renowned for interfering with the immune system of their hosts. To sidestep antigen presentation and destruction by CD8(+) T cells, these viruses reduce expression of major histocompatibility complex class I (MHC I) molecules. However, this process sensitizes the virus-i...

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Detalles Bibliográficos
Autores principales: Babić, Marina, Pyzik, Michal, Zafirova, Biljana, Mitrović, Maja, Butorac, Višnja, Lanier, Lewis L., Krmpotić, Astrid, Vidal, Silvia M., Jonjić, Stipan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989764/
https://www.ncbi.nlm.nih.gov/pubmed/21078887
http://dx.doi.org/10.1084/jem.20100921