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Extracellular NAD(+) shapes the Foxp3(+) regulatory T cell compartment through the ART2–P2X7 pathway
CD4(+)CD25(+)FoxP3(+) regulatory T cells (T reg cells) play a major role in the control of immune responses but the factors controlling their homeostasis and function remain poorly characterized. Nicotinamide adenine dinucleotide (NAD(+)) released during cell damage or inflammation results in ART2.2...
Autores principales: | Hubert, Sandra, Rissiek, Björn, Klages, Katjana, Huehn, Jochen, Sparwasser, Tim, Haag, Friedrich, Koch-Nolte, Friedrich, Boyer, Olivier, Seman, Michel, Adriouch, Sahil |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989765/ https://www.ncbi.nlm.nih.gov/pubmed/20975043 http://dx.doi.org/10.1084/jem.20091154 |
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