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Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics
The real-time dynamics of the T cell receptor (TCR) reflect antigen detection and T cell signaling, providing valuable insight into the evolving events of the immune response. Despite considerable advances in studying TCR dynamics in simplified systems in vitro, live imaging of subcellular signaling...
Autores principales: | Friedman, Rachel S., Beemiller, Peter, Sorensen, Caitlin M., Jacobelli, Jordan, Krummel, Matthew F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989766/ https://www.ncbi.nlm.nih.gov/pubmed/21041455 http://dx.doi.org/10.1084/jem.20091201 |
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