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Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity
Sensitization to contact allergens requires activation of the innate immune system by endogenous danger signals. However, the mechanisms through which contact allergens activate innate signaling pathways are incompletely understood. In this study, we demonstrate that mice lacking the adenosine triph...
Autores principales: | Weber, Felix C., Esser, Philipp R., Müller, Tobias, Ganesan, Jayanthi, Pellegatti, Patrizia, Simon, Markus M., Zeiser, Robert, Idzko, Marco, Jakob, Thilo, Martin, Stefan F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989767/ https://www.ncbi.nlm.nih.gov/pubmed/21059855 http://dx.doi.org/10.1084/jem.20092489 |
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