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IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo
Inhibitor of κB (IκB) β (IκBβ) represents one of the major primary regulators of NF-κB in mammals. In contrast to the defined regulatory interplay between NF-κB and IκBα, much less is known about the biological function of IκBβ. To elucidate the physiological role of IκBβ in NF-κB signaling in vivo,...
Autores principales: | Scheibel, Melanie, Klein, Bettina, Merkle, Heidrun, Schulz, Manon, Fritsch, Ralph, Greten, Florian R., Arkan, Melek C., Schneider, Günter, Schmid, Roland M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989768/ https://www.ncbi.nlm.nih.gov/pubmed/20975042 http://dx.doi.org/10.1084/jem.20100864 |
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