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Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression
Graft-versus-host disease (GVHD) causes significant morbidity and mortality in allogeneic hematopoietic stem cell transplantation (aHSCT), preventing its broader application to non–life-threatening diseases. We show that a single administration of a nondepleting monoclonal antibody specific for the...
Autores principales: | Albring, Jörn C., Sandau, Michelle M., Rapaport, Aaron S., Edelson, Brian T., Satpathy, Ansuman, Mashayekhi, Mona, Lathrop, Stephanie K., Hsieh, Chyi-Song, Stelljes, Matthias, Colonna, Marco, Murphy, Theresa L., Murphy, Kenneth M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989771/ https://www.ncbi.nlm.nih.gov/pubmed/21078889 http://dx.doi.org/10.1084/jem.20102017 |
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