A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling

The cytokine B cell activating factor (BAFF) and its receptor, BAFF receptor (BAFF-R), modulate signaling cascades critical for B cell development and survival. We identified a novel mutation in TNFRSF13C, the gene encoding human BAFF-R, that is present in both tumor and germline tissue from a subse...

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Detalles Bibliográficos
Autores principales: Hildebrand, Joanne M., Luo, Zhenghua, Manske, Michelle K., Price-Troska, Tammy, Ziesmer, Steven C., Lin, Wai, Hostager, Bruce S., Slager, Susan L., Witzig, Thomas E., Ansell, Stephen M., Cerhan, James R., Bishop, Gail A., Novak, Anne J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989778/
https://www.ncbi.nlm.nih.gov/pubmed/21041452
http://dx.doi.org/10.1084/jem.20100857

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