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Down-regulation of core 1 β1,3-galactosyltransferase and Cosmc by Th2 cytokine alters O-glycosylation of IgA1

Background. Patients with IgA nephropathy (IgAN) have an increased amount of abnormally O-glycosylated IgA1 in circulation, in glomerular deposits and produced by tissue cells in vitro. Although increased production of Th2 cytokines by peripheral blood lymphocytes and a functional abnormality of cor...

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Detalles Bibliográficos
Autores principales:	Yamada, Koshi, Kobayashi, Noriyoshi, Ikeda, Tomomi, Suzuki, Yusuke, Tsuge, Toshinao, Horikoshi, Satoshi, Emancipator, Steven N., Tomino, Yasuhiko
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989791/ https://www.ncbi.nlm.nih.gov/pubmed/20551088 http://dx.doi.org/10.1093/ndt/gfq325

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