IFN-γ Upregulates Survivin and Ifi202 Expression to Induce Survival and Proliferation of Tumor-Specific T Cells

BACKGROUND: A common procedure in human cytotoxic T lymphocyte (CTL) adoptive transfer immunotherapy is to expand tumor-specific CTLs ex vivo using CD3 mAb prior to transfer. One of the major obstacles of CTL adoptive immunotherapy is a lack of CTL persistence in the tumor-bearing host after transfe...

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Detalles Bibliográficos
Autores principales: Zimmerman, Mary, Yang, Dafeng, Hu, Xiaolin, Liu, Feiyan, Singh, Nagendra, Browning, Darren, Ganapathy, Vadivel, Chandler, Phillip, Choubey, Divaker, Abrams, Scott I., Liu, Kebin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989915/
https://www.ncbi.nlm.nih.gov/pubmed/21124930
http://dx.doi.org/10.1371/journal.pone.0014076

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