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Exploring the Link between Germline and Somatic Genetic Alterations in Breast Carcinogenesis

Recent genome-wide association studies (GWASs) have identified candidate genes contributing to cancer risk through low-penetrance mutations. Many of these genes were unexpected and, intriguingly, included well-known players in carcinogenesis at the somatic level. To assess the hypothesis of a germli...

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Detalles Bibliográficos
Autores principales: Bonifaci, Núria, Górski, Bohdan, Masojć, Bartlomiej, Wokołorczyk, Dominika, Jakubowska, Anna, Dębniak, Tadeusz, Berenguer, Antoni, Serra Musach, Jordi, Brunet, Joan, Dopazo, Joaquín, Narod, Steven A., Lubiński, Jan, Lázaro, Conxi, Cybulski, Cezary, Pujana, Miguel Angel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989917/
https://www.ncbi.nlm.nih.gov/pubmed/21124932
http://dx.doi.org/10.1371/journal.pone.0014078