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The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model

BACKGROUND: Cancer metastasis contributes significantly to cancer mortality and is facilitated by lymphangiogenesis and angiogenesis. A new splicing variant, endogenous soluble vascular endothelial growth factor receptor-2 (esVEGFR-2) that we recently identified is an endogenous selective inhibitor...

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Detalles Bibliográficos
Autores principales: Shibata, Masa-Aki, Ambati, Jayakrishna, Shibata, Eiko, Albuquerque, Romulo JC, Morimoto, Junji, Ito, Yuko, Otsuki, Yoshinori
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989928/
https://www.ncbi.nlm.nih.gov/pubmed/21047425
http://dx.doi.org/10.1186/1741-7015-8-69