Antigen processing for MHC presentation by autophagy

Autophagy delivers cytoplasmic constituents for lysosomal degradation. This catabolic pathway can be used to deliver intracellular antigens for major histocompatibility complex (MHC) class II presentation. In addition, recent evidence suggests that it also facilitates the processing of extracellular...

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Detalles Bibliográficos
Autor principal: Münz, Christian
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990412/
https://www.ncbi.nlm.nih.gov/pubmed/21173848
http://dx.doi.org/10.3410/B2-61
Descripción
Sumario:Autophagy delivers cytoplasmic constituents for lysosomal degradation. This catabolic pathway can be used to deliver intracellular antigens for major histocompatibility complex (MHC) class II presentation. In addition, recent evidence suggests that it also facilitates the processing of extracellular antigens for both MHC class I and II presentation.

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