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Roles of ADF/cofilin in actin polymerization and beyond

In collaboration or competition with many other actin-binding proteins, the actin-depolymerizing factor/cofilins integrate transmembrane signals to coordinate the spatial and temporal organization of actin filament assembly/disassembly (dynamics). In addition, newly discovered effects of these prote...

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Detalles Bibliográficos
Autores principales: Bamburg, James R, Bernstein, Barbara W
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990448/
https://www.ncbi.nlm.nih.gov/pubmed/21173851
http://dx.doi.org/10.3410/B2-62
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author Bamburg, James R
Bernstein, Barbara W
author_facet Bamburg, James R
Bernstein, Barbara W
author_sort Bamburg, James R
collection PubMed
description In collaboration or competition with many other actin-binding proteins, the actin-depolymerizing factor/cofilins integrate transmembrane signals to coordinate the spatial and temporal organization of actin filament assembly/disassembly (dynamics). In addition, newly discovered effects of these proteins in lipid metabolism, gene regulation, and apoptosis suggest that their roles go well beyond regulating the cytoskeleton.
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spelling pubmed-29904482010-12-20 Roles of ADF/cofilin in actin polymerization and beyond Bamburg, James R Bernstein, Barbara W F1000 Biol Rep Review Article In collaboration or competition with many other actin-binding proteins, the actin-depolymerizing factor/cofilins integrate transmembrane signals to coordinate the spatial and temporal organization of actin filament assembly/disassembly (dynamics). In addition, newly discovered effects of these proteins in lipid metabolism, gene regulation, and apoptosis suggest that their roles go well beyond regulating the cytoskeleton. Faculty of 1000 Ltd 2010-08-19 /pmc/articles/PMC2990448/ /pubmed/21173851 http://dx.doi.org/10.3410/B2-62 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Bamburg, James R
Bernstein, Barbara W
Roles of ADF/cofilin in actin polymerization and beyond
title Roles of ADF/cofilin in actin polymerization and beyond
title_full Roles of ADF/cofilin in actin polymerization and beyond
title_fullStr Roles of ADF/cofilin in actin polymerization and beyond
title_full_unstemmed Roles of ADF/cofilin in actin polymerization and beyond
title_short Roles of ADF/cofilin in actin polymerization and beyond
title_sort roles of adf/cofilin in actin polymerization and beyond
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990448/
https://www.ncbi.nlm.nih.gov/pubmed/21173851
http://dx.doi.org/10.3410/B2-62
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