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Roles of ADF/cofilin in actin polymerization and beyond
In collaboration or competition with many other actin-binding proteins, the actin-depolymerizing factor/cofilins integrate transmembrane signals to coordinate the spatial and temporal organization of actin filament assembly/disassembly (dynamics). In addition, newly discovered effects of these prote...
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Formato: | Texto |
Lenguaje: | English |
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Faculty of 1000 Ltd
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990448/ https://www.ncbi.nlm.nih.gov/pubmed/21173851 http://dx.doi.org/10.3410/B2-62 |
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author | Bamburg, James R Bernstein, Barbara W |
author_facet | Bamburg, James R Bernstein, Barbara W |
author_sort | Bamburg, James R |
collection | PubMed |
description | In collaboration or competition with many other actin-binding proteins, the actin-depolymerizing factor/cofilins integrate transmembrane signals to coordinate the spatial and temporal organization of actin filament assembly/disassembly (dynamics). In addition, newly discovered effects of these proteins in lipid metabolism, gene regulation, and apoptosis suggest that their roles go well beyond regulating the cytoskeleton. |
format | Text |
id | pubmed-2990448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Faculty of 1000 Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-29904482010-12-20 Roles of ADF/cofilin in actin polymerization and beyond Bamburg, James R Bernstein, Barbara W F1000 Biol Rep Review Article In collaboration or competition with many other actin-binding proteins, the actin-depolymerizing factor/cofilins integrate transmembrane signals to coordinate the spatial and temporal organization of actin filament assembly/disassembly (dynamics). In addition, newly discovered effects of these proteins in lipid metabolism, gene regulation, and apoptosis suggest that their roles go well beyond regulating the cytoskeleton. Faculty of 1000 Ltd 2010-08-19 /pmc/articles/PMC2990448/ /pubmed/21173851 http://dx.doi.org/10.3410/B2-62 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes |
spellingShingle | Review Article Bamburg, James R Bernstein, Barbara W Roles of ADF/cofilin in actin polymerization and beyond |
title | Roles of ADF/cofilin in actin polymerization and beyond |
title_full | Roles of ADF/cofilin in actin polymerization and beyond |
title_fullStr | Roles of ADF/cofilin in actin polymerization and beyond |
title_full_unstemmed | Roles of ADF/cofilin in actin polymerization and beyond |
title_short | Roles of ADF/cofilin in actin polymerization and beyond |
title_sort | roles of adf/cofilin in actin polymerization and beyond |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990448/ https://www.ncbi.nlm.nih.gov/pubmed/21173851 http://dx.doi.org/10.3410/B2-62 |
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