Advances in the prevention, management, and treatment of community-acquired pneumonia

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Despite the availability of powerful antibiotics, community-acquired pneumonia (CAP) remains one of the leading reasons for morbidity and mortality worldwide, and despite the availability of powerful antibiotics, there has been only little improvement in case fatality rates for many years. Consequen...

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Detalles Bibliográficos
Autores principales: Pletz, Mathias W, Welte, Tobias, Ott, Sebastian R
Formato: Texto
Lenguaje:English
Publicado: Medicine Reports Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990450/
https://www.ncbi.nlm.nih.gov/pubmed/21173853
http://dx.doi.org/10.3410/M2-53
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author Pletz, Mathias W
Welte, Tobias
Ott, Sebastian R
author_facet Pletz, Mathias W
Welte, Tobias
Ott, Sebastian R
author_sort Pletz, Mathias W
collection PubMed
description Despite the availability of powerful antibiotics, community-acquired pneumonia (CAP) remains one of the leading reasons for morbidity and mortality worldwide, and despite the availability of powerful antibiotics, there has been only little improvement in case fatality rates for many years. Consequently, it cannot be expected that novel antibiotics will substantially improve outcomes in CAP. Therefore, this review focuses on novel approaches that may reduce CAP-related mortality: the impact of immunomodulation by macrolides and fluoroquinolones and the prevention of CAP by pneumococcal vaccines.
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spelling pubmed-29904502010-12-20 Advances in the prevention, management, and treatment of community-acquired pneumonia Pletz, Mathias W Welte, Tobias Ott, Sebastian R F1000 Med Rep Review Article Despite the availability of powerful antibiotics, community-acquired pneumonia (CAP) remains one of the leading reasons for morbidity and mortality worldwide, and despite the availability of powerful antibiotics, there has been only little improvement in case fatality rates for many years. Consequently, it cannot be expected that novel antibiotics will substantially improve outcomes in CAP. Therefore, this review focuses on novel approaches that may reduce CAP-related mortality: the impact of immunomodulation by macrolides and fluoroquinolones and the prevention of CAP by pneumococcal vaccines. Medicine Reports Ltd 2010-07-22 /pmc/articles/PMC2990450/ /pubmed/21173853 http://dx.doi.org/10.3410/M2-53 Text en © 2010 Medicine Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Pletz, Mathias W
Welte, Tobias
Ott, Sebastian R
Advances in the prevention, management, and treatment of community-acquired pneumonia
title Advances in the prevention, management, and treatment of community-acquired pneumonia
title_full Advances in the prevention, management, and treatment of community-acquired pneumonia
title_fullStr Advances in the prevention, management, and treatment of community-acquired pneumonia
title_full_unstemmed Advances in the prevention, management, and treatment of community-acquired pneumonia
title_short Advances in the prevention, management, and treatment of community-acquired pneumonia
title_sort advances in the prevention, management, and treatment of community-acquired pneumonia
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990450/
https://www.ncbi.nlm.nih.gov/pubmed/21173853
http://dx.doi.org/10.3410/M2-53
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AT ottsebastianr advancesinthepreventionmanagementandtreatmentofcommunityacquiredpneumonia

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