Fungal echinocandin resistance

Mostrar otras versiones (1)

Echinocandins are the most recent introduction to the antifungal armamentarium and target the synthesis of β-(1,3)-glucan, the major structural polysaccharide of the fungal cell wall. Mechanisms have been identified that reduce the efficacy of the echinocandins: mutations of the Fks subunit of the t...

Descripción completa

Detalles Bibliográficos
Autor principal: Munro, Carol A
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990507/
https://www.ncbi.nlm.nih.gov/pubmed/21173867
http://dx.doi.org/10.3410/B2-66
_version_ 1782192478150983680
author Munro, Carol A
author_facet Munro, Carol A
author_sort Munro, Carol A
collection PubMed
description Echinocandins are the most recent introduction to the antifungal armamentarium and target the synthesis of β-(1,3)-glucan, the major structural polysaccharide of the fungal cell wall. Mechanisms have been identified that reduce the efficacy of the echinocandins: mutations of the Fks subunit of the target enzyme complex or a compensatory increase in the production of chitin, the second structural cell wall polysaccharide.
format Text
id pubmed-2990507
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Faculty of 1000 Ltd
record_format MEDLINE/PubMed
spelling pubmed-29905072010-12-20 Fungal echinocandin resistance Munro, Carol A F1000 Biol Rep Review Article Echinocandins are the most recent introduction to the antifungal armamentarium and target the synthesis of β-(1,3)-glucan, the major structural polysaccharide of the fungal cell wall. Mechanisms have been identified that reduce the efficacy of the echinocandins: mutations of the Fks subunit of the target enzyme complex or a compensatory increase in the production of chitin, the second structural cell wall polysaccharide. Faculty of 1000 Ltd 2010-09-08 /pmc/articles/PMC2990507/ /pubmed/21173867 http://dx.doi.org/10.3410/B2-66 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Munro, Carol A
Fungal echinocandin resistance
title Fungal echinocandin resistance
title_full Fungal echinocandin resistance
title_fullStr Fungal echinocandin resistance
title_full_unstemmed Fungal echinocandin resistance
title_short Fungal echinocandin resistance
title_sort fungal echinocandin resistance
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990507/
https://www.ncbi.nlm.nih.gov/pubmed/21173867
http://dx.doi.org/10.3410/B2-66
work_keys_str_mv AT munrocarola fungalechinocandinresistance

Ejemplares similares