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Phase II trial of sagopilone, a novel epothilone analog in metastatic melanoma

BACKGROUND: Sagopilone is a novel fully synthetic epothilone with promising preclinical activity and a favourable toxicity profile in phase I testing. METHODS: A phase II pharmacokinetic and efficacy trial was conducted in patients with metastatic melanoma. Patients had measurable disease, Eastern C...

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Detalles Bibliográficos
Autores principales:	DeConti, R C, Algazi, A P, Andrews, S, Urbas, P, Born, O, Stoeckigt, D, Floren, L, Hwang, J, Weber, J, Sondak, V K, Daud, A I
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990578/ https://www.ncbi.nlm.nih.gov/pubmed/20924376 http://dx.doi.org/10.1038/sj.bjc.6605931

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