Schwann cell autophagy induced by SAHA, 17-AAG, or clonazepam can reduce bortezomib-induced peripheral neuropathy

BACKGROUND: The proteasome inhibitor bortezomib has improved the survival of patients with multiple myeloma but bortezomib-induced peripheral neuropathy (BiPN) has emerged as a serious potential complication of this therapy. Animal studies suggest that bortezomib predominantly causes pathological ch...

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Detalles Bibliográficos
Autores principales: Watanabe, T, Nagase, K, Chosa, M, Tobinai, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990589/
https://www.ncbi.nlm.nih.gov/pubmed/20959823
http://dx.doi.org/10.1038/sj.bjc.6605954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990589/
https://www.ncbi.nlm.nih.gov/pubmed/20959823
http://dx.doi.org/10.1038/sj.bjc.6605954

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