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Plk4/SAK/ZYG-1 in the regulation of centriole duplication
Centrioles organize both centrosomes and cilia. Centriole duplication is tightly regulated and coordinated with the cell cycle to limit duplication to only once per cell cycle. Defects in centriole number and structure are commonly found in cancer. Plk4/SAK and the functionally related Caenorhabditi...
Autores principales: | Pearson, Chad G, Winey, Mark |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Faculty of 1000 Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990628/ https://www.ncbi.nlm.nih.gov/pubmed/21173875 http://dx.doi.org/10.3410/B2-58 |
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