Cargando…

Novel roles for IL-15 in T cell survival

Interleukin-15 (IL-15) is generally considered to be a regulator of T cell homeostasis because it works with other common gamma-chain cytokines like IL-2 and IL-7 to control the maintenance of naive and memory T cell populations. However, recent reports highlight new roles for IL-15 during the prima...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brincks, Erik L, Woodland, David L
Formato:	Texto
Lenguaje:	English
Publicado:	Faculty of 1000 Ltd 2010
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990629/ https://www.ncbi.nlm.nih.gov/pubmed/21173876 http://dx.doi.org/10.3410/B2-67

Ejemplares similares

Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice
por: Koka, Rima, et al.
Publicado: (2003)

Out-sourcing for Trans-presentation: Assessing T Cell Intrinsic and Extrinsic IL-15 Expression with Il15 Gene Reporter Mice
por: Park, Joo-Young, et al.
Publicado: (2018)

The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases
por: Waldmann, Thomas
Publicado: (2002)

IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival
por: Benito-Miguel, Marta, et al.
Publicado: (2012)

IL-15/IL-15Rα in SJS/TEN: Relevant Expression of IL15 and IL15RA in Affected Skin
por: Bellón, Teresa, et al.
Publicado: (2022)

Interleukin-15 (IL-15) and IL-15 receptor alpha fusion protein enhances antitumor activity of myxoma virus
por: Tosic, Vesna, et al.
Publicado: (2013)

Heterodimeric IL-15 in Cancer Immunotherapy
por: Bergamaschi, Cristina, et al.
Publicado: (2021)

Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis
por: Devocelle, Aurore, et al.
Publicado: (2019)

Myxoma Virus Expressing a Fusion Protein of Interleukin-15 (IL15) and IL15 Receptor Alpha Has Enhanced Antitumor Activity
por: Tosic, Vesna, et al.
Publicado: (2014)

Immunomodulatory Effects of IL-2 and IL-15; Implications for Cancer Immunotherapy
por: Yang, Ying, et al.
Publicado: (2020)

The Roles of IL-2, IL-7, and IL15 Ligands in B Cells Development from Cord Blood Mononuclear Cells
por: Aliyari, Z, et al.
Publicado: (2015)

IL-15 and its role in rheumatoid arthritis
por: Kurowska-Stolarska, M, et al.
Publicado: (2003)

A novel multimeric IL15/IL15Rα-Fc complex to enhance cancer immunotherapy
por: Xu, Hong, et al.
Publicado: (2021)

The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations
por: Laza-Stanca, Vasile, et al.
Publicado: (2011)

Coordinate Expression and Trans Presentation of Interleukin (IL)-15Rα and IL-15 Supports Natural Killer Cell and Memory CD8(+) T Cell Homeostasis
por: Burkett, Patrick R., et al.
Publicado: (2004)

TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival
por: Zhu, Lele, et al.
Publicado: (2018)

The IL-15-AKT-XBP1s signaling pathway contributes to effector functions and survival in human NK cells
por: Wang, Yufeng, et al.
Publicado: (2018)

Interleukin-15 in cancer immunotherapy: IL-15 receptor complex versus soluble IL-15 in a cancer cell-delivered murine leukemia model
por: Berger, Alexandra, et al.
Publicado: (2019)

IL-15 Enhances the Persistence and Function of BCMA-Targeting CAR-T Cells Compared to IL-2 or IL-15/IL-7 by Limiting CAR-T Cell Dysfunction and Differentiation
por: Battram, Anthony M., et al.
Publicado: (2021)

Inflammatory chemokine receptors regulate CD8(+) T cell contraction and memory generation following infection
por: Kohlmeier, Jacob E., et al.
Publicado: (2011)

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection
por: McGill, Jodi, et al.
Publicado: (2010)

IL-15 and N-803 for HIV Cure Approaches
por: Howard, J. Natalie, et al.
Publicado: (2023)

NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation
por: Clark, Sarah E., et al.
Publicado: (2019)

IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes
por: Apert, Cécile, et al.
Publicado: (2017)

An activation-induced IL-15 isoform is a natural antagonist for IL-15 function
por: Zhao, Lei, et al.
Publicado: (2016)

Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma
por: Shirley, Shawna A., et al.
Publicado: (2020)

Correction: The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations
por: Laza-Stanca, Vasile, et al.
Publicado: (2012)

Cytokine interactions in human immunodeficiency virus-infected individuals: roles of interleukin (IL)-2, IL-12, and IL-15
Publicado: (1995)

IL-2, IL-15 and IL-21 expand T cells for targeted adoptive therapy
por: Liu, Zhenjiang, et al.
Publicado: (2015)

Heterodimeric IL-15 regulates the differentiation and survival of different populations of memory T cells and the balance of effector and regulatory cells
por: Pavlakis, George N, et al.
Publicado: (2013)

IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia
por: Xu, Aizhang, et al.
Publicado: (2016)

Vaccination with Tumor Cells Expressing IL-15 and IL-15Rα Inhibit Murine Breast and Prostate Cancer
por: Morris, John C., et al.
Publicado: (2014)

Effect of IL-7 and IL-15 on T cell phenotype in myelodysplastic syndromes
por: Dong, Wen, et al.
Publicado: (2016)

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor
Publicado: (1994)

The roles of different forms of IL-15 in human melanoma progression
por: Di Matteo, Sabina, et al.
Publicado: (2023)

IL-15 enhances HIV-1 infection by promoting survival and proliferation of CCR5(+)CD4(+) T cells
por: Li, Yuhao, et al.
Publicado: (2023)

Antiviral CD4(+) memory T cells are IL-15 dependent
por: Purton, Jared F., et al.
Publicado: (2007)

Electrotransfer of IL-15/IL-15Rα complex for the treatment of established melanoma
por: Shirley, Shawna, et al.
Publicado: (2015)

IL-15 Deficient Tax Mice Reveal a Role for IL-1α in Tumor Immunity
por: Rauch, Daniel A., et al.
Publicado: (2014)

The Role of IL-13, IL-15 and Granulysin in the Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
por: Sadek, Michael, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_otaa1else819eeodplk0o45bk5