The application of massively parallel sequencing technologies in diagnostics

Massively parallel sequencing (MPS) is rapidly evolving and is starting to be utilized by the clinical field as well as diagnostics. We describe major recent advances that have come about as a result of the application of MPS in the biomedical field and the first approaches in medical genetics that...

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Detalles Bibliográficos
Autores principales: Dahl, Andreas, Mertes, Florian, Timmermann, Bernd, Lehrach, Hans
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990631/
https://www.ncbi.nlm.nih.gov/pubmed/21173878
http://dx.doi.org/10.3410/B2-59
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author Dahl, Andreas
Mertes, Florian
Timmermann, Bernd
Lehrach, Hans
author_facet Dahl, Andreas
Mertes, Florian
Timmermann, Bernd
Lehrach, Hans
author_sort Dahl, Andreas
collection PubMed
description Massively parallel sequencing (MPS) is rapidly evolving and is starting to be utilized by the clinical field as well as diagnostics. We describe major recent advances that have come about as a result of the application of MPS in the biomedical field and the first approaches in medical genetics that have made use of MPS. Without any doubt, MPS has proven to be a very powerful technique. To unravel the capabilities of MPS for patient care, the most important aspect for the acceptance of MPS within clinics and diagnostics is to guarantee that the large amount of data undergoes vitally important analyses and interpretation and is securely managed.
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spelling pubmed-29906312010-12-20 The application of massively parallel sequencing technologies in diagnostics Dahl, Andreas Mertes, Florian Timmermann, Bernd Lehrach, Hans F1000 Biol Rep Review Article Massively parallel sequencing (MPS) is rapidly evolving and is starting to be utilized by the clinical field as well as diagnostics. We describe major recent advances that have come about as a result of the application of MPS in the biomedical field and the first approaches in medical genetics that have made use of MPS. Without any doubt, MPS has proven to be a very powerful technique. To unravel the capabilities of MPS for patient care, the most important aspect for the acceptance of MPS within clinics and diagnostics is to guarantee that the large amount of data undergoes vitally important analyses and interpretation and is securely managed. Faculty of 1000 Ltd 2010-08-09 /pmc/articles/PMC2990631/ /pubmed/21173878 http://dx.doi.org/10.3410/B2-59 Text en © 2010 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Dahl, Andreas
Mertes, Florian
Timmermann, Bernd
Lehrach, Hans
The application of massively parallel sequencing technologies in diagnostics
title The application of massively parallel sequencing technologies in diagnostics
title_full The application of massively parallel sequencing technologies in diagnostics
title_fullStr The application of massively parallel sequencing technologies in diagnostics
title_full_unstemmed The application of massively parallel sequencing technologies in diagnostics
title_short The application of massively parallel sequencing technologies in diagnostics
title_sort application of massively parallel sequencing technologies in diagnostics
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990631/
https://www.ncbi.nlm.nih.gov/pubmed/21173878
http://dx.doi.org/10.3410/B2-59
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