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Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions
Metabolic coupling of Mycobacterium tuberculosis to its host is foundational to its pathogenesis. Computational genome-scale metabolic models have shown utility in integrating -omic as well as physiologic data for systemic, mechanistic analysis of metabolism. To date, integrative analysis of host–pa...
Autores principales: | Bordbar, Aarash, Lewis, Nathan E, Schellenberger, Jan, Palsson, Bernhard Ø, Jamshidi, Neema |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990636/ https://www.ncbi.nlm.nih.gov/pubmed/20959820 http://dx.doi.org/10.1038/msb.2010.68 |
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