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Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis
INTRODUCTION: Oestrogen depletion may influence onset and/or progression of osteoarthritis. We investigated in an ovariectomized mouse model the impact of oestrogen loss and oestrogen supplementation on articular cartilage and subchondral bone in tibia and patella, and assessed bone changes in osteo...
Autores principales: | Sniekers, Yvonne H, Weinans, Harrie, van Osch, Gerjo JVM, van Leeuwen, Johannes PTM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991014/ https://www.ncbi.nlm.nih.gov/pubmed/20923566 http://dx.doi.org/10.1186/ar3148 |
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