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Type I IFN and TNFα cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance

A cross-regulation between type I IFN and TNFα has been proposed recently, where both cytokines are hypothesized to counteract each other. According to this model, different autoimmune diseases can be viewed as disequilibrium between both cytokines. As this model may have important clinical implicat...

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Detalles Bibliográficos
Autores principales: Cantaert, Tineke, Baeten, Dominique, Tak, Paul P, van Baarsen, Lisa GM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991015/
https://www.ncbi.nlm.nih.gov/pubmed/21062511
http://dx.doi.org/10.1186/ar3150