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Adrenomedullin increases fibroblast-like synoviocyte adhesion to extracellular matrix proteins by upregulating integrin activation
INTRODUCTION: Rheumatoid arthritis (RA) is characterized by bone and cartilage invasion by fibroblast-like synoviocytes (FLSs). Adrenomedullin, a peptide with anabolic and antiapoptotic properties, is secreted by rheumatoid FLSs. Adrenomedullin also increases the expression of adhesion molecules in...
Autores principales: | Ah Kioon, Marie-Dominique, Asensio, Carine, Ea, Hang-Korng, Uzan, Benjamin, Cohen-Solal, Martine, Lioté, Frédéric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991025/ https://www.ncbi.nlm.nih.gov/pubmed/20942979 http://dx.doi.org/10.1186/ar3160 |
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