A phase 2 randomized, double-blind study of AMG 108, a fully human monoclonal antibody to IL-1R, in patients with rheumatoid arthritis

INTRODUCTION: Preclinical work has suggested that IL-1 plays a critical role in the pathogenesis of rheumatoid arthritis (RA). The objective of the present study was to determine the effect of a long-acting IL-1 receptor inhibitor, AMG 108, in a double-blind, placebo-controlled, parallel-dosing stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Cardiel, Mario H, Tak, Paul P, Bensen, William, Burch, Francis X, Forejtova, Sarka, Badurski, Janusz E, Kakkar, Tarundeep, Bevirt, Terry, Ni, Liyun, McCroskery, Ellen, Jahreis, Angelika, Zack, Debra J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991028/
https://www.ncbi.nlm.nih.gov/pubmed/20950476
http://dx.doi.org/10.1186/ar3163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991028/
https://www.ncbi.nlm.nih.gov/pubmed/20950476
http://dx.doi.org/10.1186/ar3163

Ejemplares similares