Urokinase-type plasminogen activator and arthritis progression: contrasting roles in systemic and monoarticular arthritis models

INTRODUCTION: Urokinase-type plasminogen activator (u-PA) has been implicated in tissue destruction/remodeling. The absence of u-PA results in resistance of mice to systemic immune complex-driven arthritis models; monoarticular arthritis models involving an intra-articular (i.a.) antigen injection,...

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Detalles Bibliográficos
Autores principales: De Nardo, Christine M, Lenzo, Jason C, Pobjoy, Jarrad, Hamilton, John A, Cook, Andrew D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991036/
https://www.ncbi.nlm.nih.gov/pubmed/20973954
http://dx.doi.org/10.1186/ar3171

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