Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers

BACKGROUND: Colorectal, endometrial and upper urinary tract tumours are characteristic for Lynch syndrome (hereditary non-polyposis colon carcinoma, HNPCC). The aim of the present study was to establish whether carriers of mutations in mismatch repair genes MLH1, MSH2 or MSH6 are at increased risk o...

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Detalles Bibliográficos
Autores principales: van der Post, R S, Kiemeney, L A, Ligtenberg, M J L, Witjes, J A, Hulsbergen-van de Kaa, C A, Bodmer, D, Schaap, L, Kets, C M, van Krieken, J H J M, Hoogerbrugge, N
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991077/
https://www.ncbi.nlm.nih.gov/pubmed/20591884
http://dx.doi.org/10.1136/jmg.2010.076992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991077/
https://www.ncbi.nlm.nih.gov/pubmed/20591884
http://dx.doi.org/10.1136/jmg.2010.076992

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